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Physics and Astronomy "Ettore Majorana"

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Alessandro La Ferlita

PhD Student
PhD in Complex Systems for Physical, Socio-economic and Life Sciences - 33° cycle
Contacts

Office: DMI 35
Email: alessandro.laferlita@unict.it
Phone: 095 7383087

Computational biologist specialized in the analysis of transcriptomic data produced by several high throughput technologies such as Next Generation Sequencing (NGS), microarray and Real-Time PCR, and in the analysis of proteomics and metabolomics data. Specifically, his research activity is focused on the development of new bioinformatics tools for the analysis of several classes of non-coding RNAs (ncRNAs) from RNA-Seq data and in the study of their involvement in several tumor types.

  1. La Ferlita A, Alaimo S, Veneziano D, Nigita G, Balatti V, Croce CM, Ferro A, Pulvirenti A. Identification of tRNA derived ncRNAs in TCGA and NCI 60 panel cell lines and development of the public database tRFexplorer. Database. 2019. doi: 10.1093/database/baz115

  2. Di Bella S, La Ferlita A, Carapezza G, Alaimo S, Isacchi A, Ferro A, Pulvirenti A, Bosotti R. A benchmarking of pipelines for detecting ncRNAs from RNA Seq data. Briefings in Bioinformatics. 2019. doi: 10.1093/bib/bbz110

  3. Alaimo S, Micale G, La Ferlita A, Ferro A, Pulvirenti A. Computational Methods to Investigate the Impact of miRNAs on Pathways. Methods Mol Biol. 2019. doi: 10.1007/978-1-4939-9207-2_11.

  4. Battaglia R, Palini S, Vento ME, La Ferlita A, Lo Faro MJ, Caroppo E, Borzì P, Falzone L, Barbagallo D, Ragusa M, Scalia M, D'Amato G, Scollo P, Musumeci P, Purrello M, Gravotta E, Di Pietro C. Identification of extracellular vesicles and characterization of miRNA expression profiles in human blastocoel fluid. Sci Rep. 2019. doi: 10.1038/s41598-018-36452-7.

  5. La Ferlita A, Battaglia R, Andronico F, Caruso S, Cianci A, Purrello M, Di Pietro C. Non-Coding RNAs in Endometrial Physiopathology. Int J Mol Sci. 2018. doi: 10.3390/ijms19072120.

  6. Di Pietro C, Caruso S, Battaglia R, Iraci Sareri M, La Ferlita A, Strino F, Bonaventura G, Di Mauro M, Barcellona ML, Perciavalle V, Purrello M, Cianci A. MiR-27a-3p and miR-124-3p, upregulated in endometrium and serum from women affected by Chronic Endometritis, are new potential molecular markers of endometrial receptivity. Am J Reprod Immunol. 2018. doi: 10.1111/aji.12858.

  7. Battaglia R, Vento ME, Ragusa M, Barbagallo D, La Ferlita A, Di Emidio G, Borzí P, Artini PG, Scollo P, Tatone C, Purrello M, Di Pietro C. MicroRNAs Are Stored in Human MII Oocyte and Their Expression Profile Changes in Reproductive Aging. Biol Reprod. 2016. doi: 10.1095/biolreprod.116.142711.